Lofexidine is used to reduce the symptoms of withdrawal (such as chills, sweating, stomach cramps, muscle pain, sleep disorders and runny nose) during detoxification from opiates (such as heroin or morphine). It is also used for the short-term treatment of hypertension.
What is Lofexidine?
Lofexidine works by interacting with alpha2-adrenergic receptors.
How should Lofexidine be taken?
Lofexidine is typically administered orally. It can be taken alone or in combination with other drugs, such as methadone or buprenorphine. The course of treatment with lofexidine lasts from 7 to 10 days.
Side effects associated with Lofexidine
Among the possible side effects of lofexidine include the following:
- Dizziness
- Drowsiness
- Dry mouth
- Dry throat
- Slow heartbeat
It is important to contact a doctor immediately if you experience:
- Rash
- Urticaria
- Difficulty breathing
- Tightness in the chest
- Swelling of the mouth, face, lips or tongue
Contraindications and warnings associated with the use of Lofexidine
Before starting treatment with Lofexidine, it is important to tell your doctor if:
- You have any allergies to the active substance, its excipients or to any other drugs, food or various substances
- You are taking any other medications, herbal remedies or supplements
- You are suffering (or have suffered) from a slow heartbeat, low blood pressure, kidney problems or depression
- You have recently suffered from a stroke or transient ischemic attack
- You are pregnant or breast-feeding
Treatment should never be stopped abruptly because of the risk of sudden increase in blood pressure.
It is important to inform physicians, surgeons or dentists of any ongoing treatment with lofexidine.
