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Griseofulvin

Griseofulvin is an antibiotic that blocks the growth of fungi dermatophytes. It is thought to work by preventing the division of the fungus cells and the synthesis of its nucleic acids, but its mechanism of action has not been elucidated.

What is Griseofulvin?

Griseofulvin is used to treat infections of the skin such as the groin fungus, athlete's foot and ringworm, fungal infections of the scalp and the nails.

How should Griseofulvin be taken?

Typically, Griseofulvin is assumed orally in the form of tablets, capsules or liquid solutions and with a posology of 1-4 doses per day.

In general, the treatment lasts from 2 to 4 weeks for skin infections, 4 to 6 weeks for those of the hair or of the scalp, from 4 to 8 weeks for the foot, from 3 to 4 months for the nails of fingers and at least 6 months to those of the toenails.

Side effects associated with Griseofulvin

Possible side effects of Griseofulvin include:

  • headache
  • stomach discomfort
  • vomit
  • diarrhea or loose stools
  • thirst
  • fatigue
  • dizziness
  • fainting

It is important to contact a doctor immediately if you have:

  • temperature
  • sore throat
  • skin rash
  • discomfort or irritation to the mouth

 

 

 

Contraindications and warnings associated with the use of Griseofulvin

Before taking Griseofulvin, it is important to inform your doctor:

  • If you have any allergy to the active substance or any other drug
  • If you are taking any other medicinal products, herbal remedies or supplements. Mentioning in particular:  anticoagulants, oral contraceptives, cyclosporin, phenobarbital and vitamins
  • If you suffer (or have suffered) from liver disease, porphyria, lupus
  • If you have a history of alcohol abuse
  • If you are pregnant or breastfeeding

During treatment with Griseofulvin, it is better to avoid unnecessary exposure or prolonged exposure to sun and use sunglasses, sun creams and clothing appropriate to defend against sunrays.

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