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Aztreonam

Aztreonam is used to treat infections by Gram-negative bacteria, especially those that affect the meninges, the bladder, and kidneys and lung infections with Pseudomonas aeruginosa. It is also used to reduce the respiratory symptoms of cystic fibrosis.

What is Aztreonam?

Aztreonam kills Gram-negative bacteria by preventing the synthesis of their wall.

 How should Aztreonam be taken?

Aztreonam can be administered by injection into a vein, intramuscular injections or be taken by inhalation. Before the treatment it may be necessary to use a bronchodilator.

Side effects associated with Aztreonam

Aztreonam may be associated with infection by Gram-positive bacteria.

Among the other possible adverse effects are included:

  • Cough
  • Mild stomach pain
  • Nasal congestion
  • Sore throat
  • Vomiting

 You should immediately contact a doctor if taking Aztreonam triggers any of the following symptoms:

  • Rash
  • Urticaria
  • Itchy skin
  • Difficult breathing
  • Discomfort or tightness in the chest
  • Swelling of the mouth, face, lips, or tongue
  • Fever
  • Severe or persistent cough, sore throat or stomach pain
  • Vomiting (severe or persistent)
  • Breath shortness
  • Wheezing

Contraindications and warnings associated with the use of Aztreonam

Aztreonam should not be taken in case of FEV-1 less than 25% or greater than 75% and in case of infection by Burkholderia cepacia.

Moreover, before starting the treatment it is important to tell your doctor if:

  • You have any allergies to the active substance, its ingredients, other drugs (especially penicillins, cephalosporins or carbapenems), food or any other substance
  • You are taking other medications, herbal remedies and supplements
  • You suffer (or have suffered) from any diseases or health conditions
  • You are pregnant or breastfeeding
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