{"id":81649,"date":"2018-06-18T10:08:00","date_gmt":"2018-06-18T10:08:00","guid":{"rendered":"http:\/\/humanitasnet-new.local\/enciclopedia\/pindolol-2\/"},"modified":"2018-06-18T10:08:00","modified_gmt":"2018-06-18T10:08:00","slug":"pindolol-2","status":"publish","type":"enciclopedia","link":"https:\/\/humanitas-net.humweb.webiz.team\/sr\/wiki\/pindolol-2\/","title":{"rendered":"Pindolol"},"content":{"rendered":"

Pindolol\u00a0 se primenjuje\u00a0 u le\u010denju angine pectoris, kardijalnim aritmijama i hipertenziji.<\/p>\n

 <\/p>\n

\u0160ta je Pindolol ?<\/h2>\n

 <\/p>\n

Pindolol je ne-selektivni antihipertenziv, antiadrenergi\u010dki beta blokator receptora 1 (na nivou sr\u010danog mi\u0161i\u0107a) kao i beta 2 (na vaskularnom i bronhijalnom nivou), te se naziva i\u00a0 \u2018\u2019beta-adrenergi\u010dki blokator\u2019\u2019 ili \u2018\u2019beta-bloker\u2019\u2019.<\/p>\n

 <\/p>\n

Efekat beta-receptoa 1 sastoji se u redukciji sr\u010dane aktivnosti usled sni\u017eene stimualcije identi\u010dnih receptora. Redukcija brzine kao i kontraktilnosti snage sr\u010danog mi\u0161i\u0107a tj. Impulsa kroz knduktivni sistem srca, odgovor sr\u010danog mi\u0161i\u0107a na stres i fizi\u010dku aktivnost je redukovana i koronarni protok je pobolj\u0161an.<\/p>\n

Sa druge strane, efekat na beta 2 receptore dovodi do inhibicije vazodilatacije i bronhodilatatora.<\/p>\n

 <\/p>\n

Intrinzi\u010dka simpatikomimeti\u010dka aktivnost ovog leka, zahvaljuju\u0107i aktivaciji simpati\u010dkog tonusa, redukuje bradikardiju na minimum, \u0161to mo\u017ee uticati na pojavu ne\u017eeljenih efekata baziranih na beta-blokatorima.<\/p>\n

 <\/p>\n

Kako se primenjuje Pindolol ?<\/h2>\n

 <\/p>\n

Pindololje komercijalno dostupan za peroralnu upotrebu.<\/p>\n

 <\/p>\n

Ne\u017eeljeni efekti udru\u017eeni sa Pindololom<\/h2>\n

 <\/p>\n

Primena Pindolola naj\u010de\u0161\u0107e se dobro toleri\u0161e i njena intrinzi\u010dka simpatikomimeti\u010dka aktivnostte dovodi do redukcije sr\u010danog rada na minimum usled inhibiaju\u0107ih efekata klasi\u010dne terapije bazirane na beta- blokatorima.<\/p>\n

 <\/p>\n

Ne\u017eeljeni efekti mogu biti rezultat primene Pindolola (svi tranzitoni klini\u010dki zna\u010dajni efekti) mogu podrazumevati: gastrointestinalne poreme\u0107aje (mu\u010dninu, povra\u0107anje, dijareju), malaksalost, glavobolju, vrtoglavicu, i hipersenzitivnost na aktivnu supstancu u vidu ko\u017enih reakcija.<\/p>\n

Kontraindikacije i mere opreza udru\u017eene sa primenom Pindolola<\/h2>\n

 <\/p>\n

Administracija Pindolola kod trudnica mo\u017ee zahtevati detaljnu evaluaciju pozitivnih efekata na maj\u010dino zdravlje kao i rizike na novoro\u0111eno dete, ali se naj\u010de\u0161\u0107e ne preporu\u010duje tokom trudno\u0107e. Iako Pindolol ne sadr\u017ei embriotoksi\u010dne supstance, i dalje\u00a0 je mogu\u0107a pojava ne\u017eeljenih efekata kao \u0161to su hemodinamski i metaboli\u010dki poreme\u0107aji koji mogu kompromitovati zdravstveno stanje fetusa.<\/p>\n

 <\/p>\n

Budu\u0107i da jo\u0161 uvek ne postoji dovoljno nau\u010dnih dokaza u vezi sa akumulacijom Pindolola u maj\u010dinom mleku, njegova primena je kontraindikovana tokom dojenja.<\/p>\n

 <\/p>\n

 <\/p>\n

 <\/p>\n","protected":false},"featured_media":0,"parent":0,"template":"","Example":[1796],"class_list":["post-81649","enciclopedia","type-enciclopedia","status-publish","hentry","enciclopedia_category-aktivni-sastojci"],"yoast_head":"\nPindolol - Humanitas.net<\/title>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"sr_RS\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Pindolol - Humanitas.net\" \/>\n<meta property=\"og:description\" content=\"Pindolol\u00a0 se primenjuje\u00a0 u le\u010denju angine pectoris, kardijalnim aritmijama i hipertenziji.   \u0160ta je Pindolol ?   Pindolol je ne-selektivni antihipertenziv, antiadrenergi\u010dki beta blokator receptora 1 (na nivou sr\u010danog mi\u0161i\u0107a) kao i beta 2 (na vaskularnom i bronhijalnom nivou), te se naziva i\u00a0 \u2018\u2019beta-adrenergi\u010dki blokator\u2019\u2019 ili \u2018\u2019beta-bloker\u2019\u2019.   Efekat beta-receptoa 1 sastoji se u redukciji […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/humanitas-net.humweb.webiz.team\/sr\/wiki\/pindolol-2\/\" \/>\n<meta property=\"og:site_name\" content=\"Humanitas.net\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/HumanitasInternational\/\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:site\" content=\"@humanitasmilano\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/humanitas-net.humweb.webiz.team\/sr\/wiki\/pindolol-2\/\",\"url\":\"https:\/\/humanitas-net.humweb.webiz.team\/sr\/wiki\/pindolol-2\/\",\"name\":\"Pindolol - Humanitas.net\",\"isPartOf\":{\"@id\":\"https:\/\/humanitas-net.humweb.webiz.team\/#website\"},\"datePublished\":\"2018-06-18T10:08:00+00:00\",\"dateModified\":\"2018-06-18T10:08:00+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/humanitas-net.humweb.webiz.team\/sr\/wiki\/pindolol-2\/#breadcrumb\"},\"inLanguage\":\"sr-RS\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/humanitas-net.humweb.webiz.team\/sr\/wiki\/pindolol-2\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/humanitas-net.humweb.webiz.team\/sr\/wiki\/pindolol-2\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/humanitas-net.humweb.webiz.team\/sr\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Enciclopedia\",\"item\":\"https:\/\/humanitas-net.humweb.webiz.team\/enciclopedia\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Pindolol\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/humanitas-net.humweb.webiz.team\/#website\",\"url\":\"https:\/\/humanitas-net.humweb.webiz.team\/\",\"name\":\"Humanitas.net\",\"description\":\"Humanitas Hospital\",\"publisher\":{\"@id\":\"https:\/\/humanitas-net.humweb.webiz.team\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/humanitas-net.humweb.webiz.team\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"sr-RS\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/humanitas-net.humweb.webiz.team\/#organization\",\"name\":\"Humanitas\",\"url\":\"https:\/\/humanitas-net.humweb.webiz.team\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"sr-RS\",\"@id\":\"https:\/\/humanitas-net.humweb.webiz.team\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/humanitas-net.humweb.webiz.team\/wp-content\/uploads\/2025\/01\/new-humanitas-logo-1.svg\",\"contentUrl\":\"https:\/\/humanitas-net.humweb.webiz.team\/wp-content\/uploads\/2025\/01\/new-humanitas-logo-1.svg\",\"width\":1,\"height\":1,\"caption\":\"Humanitas\"},\"image\":{\"@id\":\"https:\/\/humanitas-net.humweb.webiz.team\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.facebook.com\/HumanitasInternational\/\",\"https:\/\/x.com\/humanitasmilano\"]}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Pindolol - Humanitas.net","robots":{"index":"noindex","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"og_locale":"sr_RS","og_type":"article","og_title":"Pindolol - Humanitas.net","og_description":"Pindolol\u00a0 se primenjuje\u00a0 u le\u010denju angine pectoris, kardijalnim aritmijama i hipertenziji.   \u0160ta je Pindolol ? 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