{"id":71496,"date":"2017-11-08T12:35:17","date_gmt":"2017-11-08T12:35:17","guid":{"rendered":"http:\/\/humanitasnet-new.local\/malattie\/leukemija-vlasastih-celija\/"},"modified":"2025-01-13T02:59:02","modified_gmt":"2025-01-13T02:59:02","slug":"leukemija-vlasastih-celija","status":"publish","type":"disease","link":"https:\/\/humanitas-net.humweb.webiz.team\/sr\/diseases\/leukemija-vlasastih-celija\/","title":{"rendered":"Leukemija vlasastih \u0107elija"},"content":{"rendered":"

Leukemija vlasastih \u0107elija je podvrsta hroni\u010dne mijeloidne leukemije, odnosno bolesti maligniteta krvi i ko\u0161tane sr\u017ei. Ova vrsta leukemije je izuzetno retka i javlja se kada ko\u0161tana sr\u017e po\u010dne nekontrolisano da proizvodi limfocite. Limfociti su \u0107elije krvi, i zajedno sa granulocitima i monocitima \u010dine bela krvna zrnca. Funkcija belih krvnih zrnaca je imunolo\u0161ka, \u0161to zna\u010di da oni predstavljaju prvi red odbrane organizma od bolesti i infekcija.<\/p>\n

Kada ko\u0161tana sr\u017e po\u010dne da nekontrolisano proizvodi leukocite, dolazi do disbalansa u odnosu krvnih \u0107elija. Preteranom akumulacijom B \u0107elija dolazi do smanjenja proizvodnje granulocita, monocita, eritrocita i trombocita, kao i stvaranja kancerogenog tumora u krvi ili ko\u0161tanoj sr\u017ei.<\/p>\n

Leukemija vlasastih \u0107elija se uglavnom javlja kod mu\u0161karaca srednjeg i starijeg doba. \u017dene, mladi ljudi i deca su manje podlo\u017eni ovoj vrsti leukemije.<\/p>\n

Ova vrsta leukemije se svrstava pod progresivne hroni\u010dne bolesti, \u0161to zna\u010di da se u najve\u0107em broju slu\u010dajeva ne mo\u017ee potpuno izle\u010diti ve\u0107 samo dovesti do remisije.<\/p>\n

 <\/p>\n

Simtpomi<\/strong><\/h2>\n

Rani stadijumi leukemije vlasastih \u0107elija \u010desto nemaju nikakve simptome, i onda se uvidi tek prilikom rutinskog va\u0111enja krvi. Ukoliko do\u0111e do pojave simptoma, to su uglavnom:<\/p>\n

\u00b7\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Umor<\/p>\n

\u00b7\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Iscrpljenost<\/p>\n

\u00b7\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Lako nastajanje podliva i masnica<\/p>\n

\u00b7\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 U\u010destale infekcije<\/p>\n

\u00b7\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Gubitak telesne te\u017eine<\/p>\n

\u00b7\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Slabost<\/p>\n

 <\/p>\n

Uzroci<\/strong><\/h2>\n

Kao i sve vrste karcinoma, leukemija nastaje kada mutacije u DNK \u0107elija dovede do njihovog nekontrolisanog umno\u017eavanja i onemogu\u0107i njihovo normalno odumiranje i raspadanje. Za\u0161to se javljaju ove mutacije na DNK leukocita i dalje nije poznato.<\/p>\n

<\/h2>\n

Faktori rizika<\/strong><\/h2>\n

Faktori koji mogu pove\u0107ati rizik od nastajanja leukemije vlasastih \u0107elija su:<\/p>\n

\u00b7\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Izlo\u017eenost radijaciji \u2013 rad sa rendgenima ili primanje i davanje terapije radijacijom<\/p>\n

\u00b7\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Izlo\u017eenost toksi\u010dnim industrijskim ili poljoprivrednim hemikalijama<\/p>\n

\u00b7\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Izlo\u017eenost industrijskoj pra\u0161ini<\/p>\n

\u00b7\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Poreklo \u2013 mu\u0161ka populacija A\u0161kenazi jevreja je podlo\u017enija ovoj vrsti leukemije od svih drugih rasa i naroda<\/p>\n

<\/h2>\n

Komplikacije<\/strong><\/h2>\n

Ukoliko se leukemija vlasastih \u0107elija ne le\u010di, broj malignih leukocita mo\u017ee prema\u0161iti broj svih ostalih zdravih \u0107elija krvi i dovesti do slede\u0107ih komplikacija:<\/p>\n

\u00b7\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Infekcije \u2013 nedovoljna koli\u010dina zdravih belih krvnih zrnaca pove\u0107ava rizik od virusnih i bakterijskih infekcija<\/p>\n

\u00b7\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Krvarenje \u2013 krv sa niskim sadr\u017eajem trombocita se te\u017ee zgru\u0161ava \u0161to mo\u017ee dovesti do nastajanja povr\u0161inskog ili unutra\u0161njeg krvarenja koje se mora zaustaviti hirur\u0161kom intervencijom<\/p>\n

\u00b7\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Anemija \u2013 nizak nivo eritrocita u krvi zna\u010di da dolazi do smanjivanja nivoa kiseonika u krvi \u0161to izaziva hroni\u010dan umor i malaksalost<\/p>\n

\u00b7\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Pove\u0107an rizik od sekundarnih karcinoma \u2013 ljudi koji boluju od leukemije vlasastih \u0107elija imaju pove\u0107an rizik od razvijanja druge vrste raka, i to naj\u010de\u0161\u0107e Neho\u010dkinovog limfoma.<\/p>\n","protected":false},"featured_media":0,"template":"","class_list":["post-71496","disease","type-disease","status-publish","hentry"],"yoast_head":"\nLeukemija vlasastih \u0107elija - Humanitas.net<\/title>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"sr_RS\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Leukemija vlasastih \u0107elija - Humanitas.net\" \/>\n<meta property=\"og:description\" content=\"Leukemija vlasastih \u0107elija je podvrsta hroni\u010dne mijeloidne leukemije, odnosno bolesti maligniteta krvi i ko\u0161tane sr\u017ei. 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