{"id":71442,"date":"2017-11-09T13:08:54","date_gmt":"2017-11-09T13:08:54","guid":{"rendered":"http:\/\/humanitasnet-new.local\/malattie\/segrenov-sindrom\/"},"modified":"2025-01-13T02:58:13","modified_gmt":"2025-01-13T02:58:13","slug":"segrenov-sindrom","status":"publish","type":"disease","link":"https:\/\/humanitas-net.humweb.webiz.team\/sr\/diseases\/segrenov-sindrom\/","title":{"rendered":"\u0160egrenov sindrom"},"content":{"rendered":"

\u0160egrenov sindrom (original Sj\u00f6gren’s) je autoimuni poreme\u0107aj. Imuni sistem tela napada \u017elezde sa spolja\u0161njim lu\u010denjem, poput pljuva\u010dnih i suznih \u017elezda. <\/span><\/p>\n

Posledice \u0160egrenovog sindroma mogu biti rasprostranjene. Neke \u017elezde postaju upaljenje, \u0161to dovodi do smanjenog lu\u010denja pljuva\u010dke ili suza, \u0161to dovodi do nastanka dva glavna simptoma \u0160egrenovog simptoma: suve o\u010di i suva usta. <\/span><\/p>\n

Kod \u017eena, kod kojih se ovaj sindrom mnogo \u010de\u0161\u0107e javlja nego kod mu\u0161karaca, \u017elezde koje vaginu odr\u017eavaju vla\u017enom tako\u0111e mogu biti ugro\u017eene sindromom, \u0161to mo\u017ee dovesti do suvo\u0107e vagine. <\/span><\/p>\n

\u0160egrenov sindrom naj\u010de\u0161\u0107e poga\u0111a osobe starosne dobi od 40 do 60 godina, uz to da \u017eene \u010dine ogromnu ve\u0107inu obolelih sa oko 90% slu\u010dajeva. \u00a0<\/span><\/p>\n

 <\/p>\n

Simptomi<\/span><\/h2>\n

Simptomi variraju od osobe do osobe i mogu da obuhvataju slede\u0107e: <\/span><\/p>\n

suvo\u0107a, pe\u010denje ili ose\u0107aj da se ima pesak u oku.<\/span><\/p>\n

suva usta.<\/span><\/p>\n

ote\u017eani govor, \u017evakanje ili gutanje.<\/span><\/p>\n

suvi ili ispucali jezik.<\/span><\/p>\n

upaljeno grlo uz mogu\u0107i ose\u0107aj pe\u010denja.<\/span><\/p>\n

suve ili ispucale usne koje se lju\u0161te.<\/span><\/p>\n

promena \u010dula mirisa i ukusa.<\/span><\/p>\n

 <\/p>\n

Uzroci<\/span><\/h2>\n

\u0160egrenov sindrom je autoimuno stanje, koje se javlja kada imuni sistem, umesto da \u0161titi telo od bolesti i iinfekcija, reaguje na neadekvatan na\u010din napadaju\u0107i sopstvena zdrava tkiva i \u0107elije. <\/span><\/p>\n

Kod \u0160egrenovog sindroma, imuni sistem napada suzne i pljuva\u010dne \u017elezde, kao i druge \u017elezde sa spolja\u0161njim lu\u010denjem po \u010ditavom telu. <\/span><\/p>\n

Uzrok ove bolesti ostaje nepozna, ali neka istra\u017eivanja ukazuju na to da bolest nataje kombinacijom genetski faktora, uticaja okoline i hormonskih faktora. <\/span><\/p>\n

Za neke osobe se smatra da su podlo\u017enije dobijanju ovog sindroma po ro\u0111enju i da neki doga\u0111aji, poput infekcija, mogu biti okida\u010d za nastanak problema sa imunim sistemom. <\/span><\/p>\n

\u0160egrenov sindrom mo\u017ee biti bilo primarni, kada se javlja sam od sebe i nije rezultat nikakvog drugog stanja, ili sekundarni, kada se razvija u kombinaciji sa drugim autoimunim oboljenjem, poput lupusa ili reumatoidnog artritisa. \u00a0<\/span><\/p>\n

 <\/p>\n

Faktori rizika<\/span><\/h2>\n

Me\u0111u faktore rizika za pojavu \u0160egrenovog sindroma su:<\/span><\/p>\n

Starosna dob – \u0160egrenov sindrom obi\u010dno se javlja kod osoba starijih od 40 godina. <\/span><\/p>\n

Pol – Mnogo je \u010de\u0161\u0107i kod \u017eena.<\/span><\/p>\n

Reumatska bolest – \u010cesta je pojava da osobe koje imaju \u0160egrenov sindrom tako\u0111e pate i od nekog reumatskog oboljenja \u2013 lupusa ili reumatoidnog artritisa.<\/span><\/p>\n

 <\/p>\n

Komplikacije<\/span><\/h2>\n

Naj\u010de\u0161\u0107a komplikacije od \u0160egrenovog sistema vezane su za o\u010di i usta. <\/span><\/p>\n

Dentalni karijes – Budu\u0107i da pljuva\u010dka \u0161titi usnu duplju od bakterija koje uzrokuju karijes, verovatnije je da \u0107e se on \u010de\u0161\u0107e javljati kod suvih usta. <\/span><\/p>\n

Gljivi\u010dna infekcija – Osobe sa \u0160egrenovim sindromom \u010de\u0161\u0107e \u0107e imati gljivi\u010dnu infekciju usta, naj\u010da\u0161\u0107e kandidom. <\/span><\/p>\n

Problemi sa vidom – Suve o\u010di mogu dovesti do osetljivosti na svetlost, zamu\u0107eni vid i \u010direve na ro\u017enja\u010di. <\/span><\/p>\n

Re\u0111e komplikacije mogu da pogode:<\/span><\/p>\n

Plu\u0107a, bubrege ili jetru – Zapaljenje mo\u017ee dovesti do pneumonije, bronhitisa ili drugih problema sa plu\u0107ima; mo\u017ee dovesti do problema sa bubrezima; a mo\u017ee da izazove i cirozu jetre ili hepatitis. <\/span><\/p>\n

Limfne \u010dvorove – Mali procenat osoba obolelih od \u0160egrenovog sindroma mogu da dobiju kancer limfnih \u010dvorova (limfom).<\/span><\/p>\n

Nerve – Mogu se javiti utrnulost, \u017emarci ili ose\u0107aj pe\u010denja u rukama ili stopalima (periferna neuropatija).<\/span><\/p>\n

 <\/p>\n

Prevencija<\/span><\/h2>\n

Nije poznato kako se mo\u017ee spre\u010diti pojava \u0160egrenovog sindroma. <\/span><\/p>\n","protected":false},"featured_media":0,"template":"","class_list":["post-71442","disease","type-disease","status-publish","hentry"],"yoast_head":"\n\u0160egrenov sindrom - Humanitas.net<\/title>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"sr_RS\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u0160egrenov sindrom - Humanitas.net\" \/>\n<meta property=\"og:description\" content=\"\u0160egrenov sindrom (original Sj\u00f6gren’s) je autoimuni poreme\u0107aj. Imuni sistem tela napada \u017elezde sa spolja\u0161njim lu\u010denjem, poput pljuva\u010dnih i suznih \u017elezda. Posledice \u0160egrenovog sindroma mogu biti rasprostranjene. 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