{"id":71364,"date":"2017-11-07T20:10:09","date_gmt":"2017-11-07T20:10:09","guid":{"rendered":"http:\/\/humanitasnet-new.local\/malattie\/karcinom-kostiju\/"},"modified":"2025-01-13T02:57:03","modified_gmt":"2025-01-13T02:57:03","slug":"karcinom-kostiju","status":"publish","type":"disease","link":"https:\/\/humanitas-net.humweb.webiz.team\/sr\/diseases\/karcinom-kostiju\/","title":{"rendered":"Karcinom kostiju"},"content":{"rendered":"

Karcinom kostiju predstavlja karcinom porekla ko\u0161tanih struktura i predstavlja izuztno redak karcinom. Sekundarni karcinom kostiju predstavlja udaljene metastaze porekla od drugih tipova karcinoma.<\/span><\/p>\n

Kosti su sa\u010dinjene od \u0107elija me\u0111usobno povezanih strukturom sa\u010dinjenom predominantno od molekula kalcijuma \u0161to ih \u010dini izuzetno jakim i otpornim na mehani\u010dku silu. Kosti su \u0161uplje strukture, sa centralnom strukturom sun\u0111eraste structure izgra\u0111ene od \u0107elija kosti. Ljudsko telo sa\u010dinjeno je od vi\u0161e od 200 kostiju. Osnovna funkcija im je da podr\u017ee telo (duga\u010dke kosti), za\u0161tite odre\u0111ene delove tela (rebarni ugao i kosti lobanje), kao i da balansiraju i omogu\u0107avaju pokrete organizma (pomo\u0107u tetiva i hrskavica kostiju).<\/span><\/p>\n

Postoji \u010detiri naj\u010de\u0161\u0107a tipa karcinoma kostiju:<\/span><\/p>\n

Osteosarkom – predstavlja naj\u010de\u0161\u0107i tip karcinoma kostiju; karakterisit\u010dan je za period adolescencije, iako mo\u017ee nastati u bilo kom \u017eivotnom dobu; naj\u010de\u0161\u0107e se razvija na osnoci duga\u010dkih kostiju kao \u0161to je butna (femur) i \u00a0potkolena kost (tibija).<\/span><\/p>\n

Eving-ov sarkom \u2013 naj\u010de\u0161\u0107i je tumor kostiju kod tinejd\u017eera; naj\u010de\u0161\u0107e se razvija u karlici, buntoj ili potkolenoj kosti.<\/span><\/p>\n

Hondrosarkom karakterisit\u010dan je za odraslo doba, u period izme\u0111u 30 i 60 godina, naj\u010de\u0161\u0107e zahvata karli\u010dne kosti, butnu, nadlakatne kosti, rameni predeo i rebra<\/span><\/p>\n

Sarkom mekih tkiva kostiju razivja se kod osoba starijih od 40 godina; I veoma je sli\u010dan osteosarkomu.<\/span><\/p>\n

 <\/p>\n

\u00a0Simptomi<\/span><\/h2>\n

Simptomatologija karcinoma kostiju izuzetno je promenljiva, u zavisnosti od tipai lokalizacije karcinoma. Simptomi su slede\u0107i:<\/span><\/p>\n

Bol u regiji tumora<\/span><\/p>\n

Otok (u slu\u010daju tumora ve\u0107ih dimenzija)<\/span><\/p>\n

Lokomotorni problem (problem sa kretanjem), u slu\u010daju zahva\u0107enosti zglobnih struktura<\/span><\/p>\n

Prelomi kostiju<\/span><\/p>\n

Gubitak na te\u017eini<\/span><\/p>\n

U re\u0111e simptome karcinoma\u00a0 kostiju spadaju :<\/span><\/p>\n

Umor<\/span><\/p>\n

Temperatura ili znojenje<\/span><\/p>\n

\u00a0<\/span><\/p>\n

Uzroci<\/span><\/h2>\n

Uzrok primarnog karcinoma kostiju jo\u0161 uvek je nepoznat.\u00a0 Prvi korak u nastanku karcinoma jeste promena u strukturi DNA poznatoj kao mutacija, koja mo\u017ee modulisati reakcije koje kontroli\u0161u \u0107elijski rast.\u00a0 Usled toga nastaje nekontrolisana deoba \u0107elija sa stvaranjem lokalne izrasline nazvane tumor.<\/span><\/p>\n

 <\/p>\n

Faktori rizika<\/span><\/h2>\n

Faktori koji pove\u0107avaju rizik za nastanak I razvoj karcinoma kostiju su malobrojni, s obziorm na nepoznat mehanizam nastanka.<\/span><\/p>\n

Faktori rizika su:<\/span><\/p>\n

Brzo-rastu\u0107e kosti \u00a0<\/span><\/p>\n

Prethodna zra\u010dna terapija<\/span><\/p>\n

Pad\u017eetovo oboljenje\u00a0 kostiju , \u010desto kod starijih osoba<\/span><\/p>\n

Retka genetska oboljenja, kao \u0161to su Li-Fraumeni sindrom<\/span><\/p>\n

Retinoblastom\u00a0 (karcinom o\u010dnih struktura kdod dece)<\/span><\/p>\n

Istra\u017eivanja su tako\u0111e potvrdila da je Eving-ov sarkom tri puta \u010de\u0161\u0107i kod novoro\u0111en\u010dadi koje su ro\u0111ene a prisutnom umbilikalnom hernijom (kilom).<\/span><\/p>\n","protected":false},"featured_media":0,"template":"","class_list":["post-71364","disease","type-disease","status-publish","hentry"],"yoast_head":"\nKarcinom kostiju - Humanitas.net<\/title>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"sr_RS\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Karcinom kostiju - Humanitas.net\" \/>\n<meta property=\"og:description\" content=\"Karcinom kostiju predstavlja karcinom porekla ko\u0161tanih struktura i predstavlja izuztno redak karcinom. Sekundarni karcinom kostiju predstavlja udaljene metastaze porekla od drugih tipova karcinoma. 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