{"id":81877,"date":"2018-07-03T11:05:30","date_gmt":"2018-07-03T11:05:30","guid":{"rendered":"http:\/\/humanitasnet-new.local\/enciclopedia\/ceftazidima\/"},"modified":"2018-07-03T11:05:30","modified_gmt":"2018-07-03T11:05:30","slug":"ceftazidima","status":"publish","type":"enciclopedia","link":"https:\/\/humanitas-net.humweb.webiz.team\/ro\/wiki\/ceftazidima\/","title":{"rendered":"Ceftazidim\u0103"},"content":{"rendered":"

Ceftazidima este un antibiotic care apar\u021bine grupului cefalosporinelor de a treia genera\u021bie. Are o activitate antimicrobian\u0103 similar\u0103 cu cea a Cefotaximei \u0219i se lupt\u0103 \u00eempotriva bacteriilor gram-pozitive \u0219i a enterobacteriilor. Ac\u021bioneaz\u0103 prin inhibarea sintezei peretelui bacterian. Similar cu alte cefalosporine, acest antibiotic are capacitatea de a se lega de enzimele transpeptidazei care servesc la crearea leg\u0103turilor dintre lan\u021burile peptidoglican (polimerii esen\u021biali pentru constituirea peretelui bacterian). La r\u00e2ndul s\u0103u, activitatea transpeptidazei previne stabilitatea peretelui celular bacterian, duc\u00e2nd la moartea celulelor bacteriene \u00een cre\u0219tere.<\/p>\n

Ce este Ceftazidima?<\/h2>\n

Ceftazidima este utilizat \u00een tratamentul urm\u0103toarelor infec\u021bii sensibile la cefalosporine la adul\u021bi, copii \u0219i sugari:
\n\u2022\u00a0 Infec\u021bii ale tractului respirator, cum ar fi pneumonia;
\n\u2022\u00a0 Infec\u021bii pulmonare la pacien\u021bii cu fibroz\u0103 chistic\u0103;
\n\u2022\u00a0 Infec\u0163ii ale tractului urinar;
\n\u2022\u00a0 Infec\u021bii ale pielii, \u021besuturilor moi, oaselor \u0219i articula\u021biilor;
\n\u2022\u00a0 infec\u021bii ale urechii;
\n\u2022\u00a0 Peritonita;
\n\u2022\u00a0 Septicemie;
\n\u2022\u00a0 Meningita<\/p>\n

Cum ar trebui luat\u0103 Ceftazidima?<\/h2>\n

Ceftazidima se administreaz\u0103 sub form\u0103 de pulbere \u0219i solvent prin injec\u021bie. Acesta poate fi administrat intramuscular, intravenos sau ca solu\u021bie de perfuzie.<\/p>\n

Reac\u021bii adverse asociate cu ceftazidima<\/h2>\n

Exist\u0103 mai multe efecte secundare cunoscute din utilizarea Ceftazidime, de\u0219i pare a fi un antibiotic bine tolerat \u00een mare m\u0103sur\u0103. Reac\u021biile adverse posibile includ urm\u0103toarele:<\/p>\n

\u2022\u00a0 Tulbur\u0103ri la nivelul locului de injectare (flebit\u0103 sau tromboflebit\u0103 cu administrare intravenoas\u0103, durere \u0219i\/sau inflama\u021bie care rezult\u0103 din administrarea intramuscular\u0103);
\n\u2022\u00a0 Reac\u021bii alergice: erup\u021bie cutanat\u0103 maculopapular\u0103 sau urticarie, m\u00e2nc\u0103rime, febr\u0103, angioedem rare \u0219i reac\u021bii anafilactice (inclusiv bronhospasm \u0219i\/sau hipotensiune arterial\u0103).
\n\u2022\u00a0 Tulbur\u0103ri gastrointestinale: diaree, grea\u021b\u0103, v\u0103rs\u0103turi, dureri abdominale, colit\u0103 mai rar\u0103 \u0219i candidoz\u0103 a cavit\u0103\u021bii bucale;
\n\u2022\u00a0 Tulbur\u0103ri genitourinare: candidoz\u0103, vaginit\u0103;
\n\u2022\u00a0 Tulbur\u0103ri neurologice: cefalee, ame\u021beli, parestezii;
\n\u2022\u00a0 Anomalii ale func\u021biei renale \u0219i hepatice
\n\u2022\u00a0 Tulbur\u0103ri hematologice (rare): leucopenie, neutropenie, agranulocitoz\u0103, trombocitopenie \u0219i limfocitoz\u0103.<\/p>\n

Contraindica\u021bii \u0219i avertismente asociate cu utilizarea Ceftazidimei<\/h2>\n

Cantitatea limitat\u0103 de date cu privire la utilizarea Ceftazidime \u00een timpul sarcinii nu eviden\u021biaz\u0103 niciun efect d\u0103un\u0103tor direct sau indirect asupra sarcinii \u00een sine, cum ar fi dezvoltarea embrionar\u0103\/fetal\u0103, na\u0219terea sau dezvoltarea postnatal\u0103. Din acest motiv, utilizarea acestui antibiotic trebuie prescris\u0103 femeilor \u00eens\u0103rcinate numai dac\u0103 beneficiul dep\u0103\u0219e\u0219te riscul. Ceftazidima se acumuleaz\u0103 \u00een laptele matern \u00een cantit\u0103\u021bi mici \u0219i, prin urmare, nu exist\u0103 nicio contraindica\u021bie pentru utilizarea acestuia \u00een timpul al\u0103pt\u0103rii.<\/p>\n

Nu s-au efectuat studii privind capacitatea de a conduce vehicule \u0219i de a folosi utilaje \u00een timp ce lua\u021bi Ceftazidime. Cu toate acestea, este recomandat s\u0103 re\u021bine\u021bi c\u0103 utilizarea medicamentului poate provoca ame\u021beli. \u00cen timpul inject\u0103rii acestui medicament, se recomand\u0103 s\u0103 se considere c\u0103 tratamentul concomitent cu doze mari de cefalosporine \u0219i medicamente nefrotoxice poate avea un efect negativ asupra func\u021biei renale.<\/p>\n

 <\/p>\n

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