{"id":70748,"date":"2017-03-30T16:00:53","date_gmt":"2017-03-30T16:00:53","guid":{"rendered":"http:\/\/humanitasnet-new.local\/malattie\/colangita-sclerozanta-primara\/"},"modified":"2025-01-13T02:48:18","modified_gmt":"2025-01-13T02:48:18","slug":"colangita-sclerozanta-primara","status":"publish","type":"disease","link":"https:\/\/humanitas-net.humweb.webiz.team\/ro\/diseases\/colangita-sclerozanta-primara\/","title":{"rendered":"Colangita sclerozant\u0103 primar\u0103"},"content":{"rendered":"

Colangita sclerozant\u0103 primar\u0103<\/strong><\/h2>\n

 <\/p>\n

Colangita sclerozant\u0103 primar\u0103 este o boal\u0103 a c\u0103ilor biliare, care transport\u0103 bila de la ficat c\u0103tre intestinul sub\u021bire. În procesul bolii în care c\u0103ile biliare din ficat devin inflamate, se îngusteaz\u0103, sunt pline de cicatrici \u0219i preveni bila din a circula în mod corespunz\u0103tor. De-a lungul timpului, aceast\u0103 inflama\u021bie scade fluxul sanguin în interior, cre\u0219te presiunia în vena port\u0103. Cicatricile îngusteaz\u0103 ducturile \u0219i pot provoca treptat leziuni hepatice grave. La majoritatea oamenilor cu CSP, boala progreseaza lent \u0219i poate duce la insuficien\u021b\u0103 hepatic\u0103, infec\u021bii repetate \u0219i tumori.<\/p>\n

 <\/p>\n

Simptome<\/strong><\/h2>\n

În stadiile incipiente, PSC este asimptomatic. colangita sclerozant\u0103 primar\u0103 este de multe ori diagnosticat\u0103 înainte de simptomele care apar atunci când un test de sânge de rutin\u0103 sau un X-ray este realizat pentru o afec\u021biune care nu are leg\u0103tur\u0103 cu aceasta \u0219i prezint\u0103 anomalii hepatice. Astfel, înainte de a avea simptome, mul\u021bi oameni continu\u0103 s\u0103 se simt\u0103 bine, în general, timp de mai mul\u021bi ani, dar nu exist\u0103 nici o modalitate sigur\u0103 de a anticipa modul rapid sau lent în care boala va progresa. Simptomele precoce includ adesea oboseal\u0103 \u0219i mânc\u0103rime. Simptomele care pot ap\u0103rea odat\u0103 cu progresele bolii includ:<\/p>\n

    \n
  • dureri în partea dreapta sus a abdomenului<\/li>\n
  • febr\u0103<\/li>\n
  • frisoane<\/li>\n
  • transpira\u021bii nocturne<\/li>\n
  • ficat m\u0103rit<\/li>\n
  • sl\u0103bire<\/li>\n
  • ochii \u0219i tegumente galbene<\/li>\n<\/ul>\n

     <\/p>\n

    Cauze<\/strong><\/h2>\n

    Nu este clar ce cauzeaz\u0103 CSP. Se crede c\u0103 poate exista o component\u0103 autoimun\u0103 a bolii, în cazul în care sistemul imunitar al organismului atac\u0103 c\u0103ile biliare în ficat \u0219i le provoac\u0103 s\u0103 devin\u0103 inflamate. O mare parte din persoanele cu CSP au, de asemenea, boala inflamatorie a intestinului, un termen generic care include colita ulcerativ\u0103 \u0219i boala Crohn. În unele cazuri, colangita sclerozant\u0103 primar\u0103 este prezent\u0103 ani buni înainte de apari\u021bia bolii inflamatorii intestinale. \u0218i rar, persoanele cu colangita sclerozant\u0103 primar\u0103 dezvolt\u0103 boala inflamatorie a intestinului numai dup\u0103 un transplant de ficat.<\/p>\n

     <\/p>\n

    Factori de risc<\/strong><\/h2>\n

    Urm\u0103toarele categorii de persoane sunt considerate cu un risc mai mare de a suferi de colangita sclerozant\u0103 primar\u0103:<\/p>\n

      \n
    • Oamenii cu vârsta cuprins\u0103 între 30 \u0219i 50 de ani.<\/li>\n
    • B\u0103rba\u021bii, mai degrab\u0103 decât femeile.<\/li>\n
    • Persoanele cu boala inflamatorie a intestinului.<\/li>\n
    • Oameni din Statele Unite \u0219i Europa de Nord au un risc mai mare de a face  colangita sclerozant\u0103 primar\u0103 decât oamenii din Asia \u0219i Europa de Sud.<\/li>\n<\/ul>\n

       <\/p>\n

      Complica\u0163ii<\/strong><\/h2>\n

      CSP este o boala progresiv\u0103, deteriorarea canalelor biliare \u0219i reducerea fluxului biliar, în cele din urm\u0103 conduce la hipertensiune portal\u0103, ciroz\u0103 \u0219i insuficien\u021b\u0103 hepatic\u0103. Complica\u021bii ale colangitei sclerozante primare pot include:<\/p>\n

        \n
      • boli de ficat;<\/li>\n
      • infec\u021bii repetate;<\/li>\n
      • hipertensiune portal\u0103;<\/li>\n
      • sub\u021bierea oaselor;<\/li>\n
      • cancer de duct biliar;<\/li>\n
      • cancer de colon<\/li>\n<\/ul>\n

         <\/p>\n

        Profilaxie<\/strong><\/h2>\n

        Cauza specific\u0103 a CSP este înc\u0103 necunoscut\u0103 \u0219i, prin urmare, nu pare a se putea preveni. <\/p>\n","protected":false},"featured_media":0,"template":"","class_list":["post-70748","disease","type-disease","status-publish","hentry"],"yoast_head":"\nColangita sclerozant\u0103 primar\u0103 - Humanitas.net<\/title>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"ro_RO\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Colangita sclerozant\u0103 primar\u0103 - Humanitas.net\" \/>\n<meta property=\"og:description\" content=\"Colangita sclerozant\u0103 primar\u0103   Colangita sclerozant\u0103 primar\u0103 este o boal\u0103 a c\u0103ilor biliare, care transport\u0103 bila de la ficat c\u0103tre intestinul sub\u021bire. 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