{"id":76113,"date":"2017-03-24T15:31:45","date_gmt":"2017-03-24T15:31:45","guid":{"rendered":"http:\/\/humanitasnet-new.local\/cure\/fosfataza-alcalina\/"},"modified":"2017-03-24T15:31:45","modified_gmt":"2017-03-24T15:31:45","slug":"fosfataza-alcalina","status":"publish","type":"cure","link":"https:\/\/humanitas-net.humweb.webiz.team\/ro\/treatments\/fosfataza-alcalina\/","title":{"rendered":"Fosfataz\u0103 alcalin\u0103"},"content":{"rendered":"

Fosfataz\u0103 alcalin\u0103<\/h2>\n

<\/h2>\n

Ce este fosfataza alcalin\u0103?<\/h2>\n

Fosfataza alcalin\u0103 (ALP) este o enzim\u0103 care catalizeaz\u0103 clivajul ortofosfatului din monoesterii ortofosforici \u00een condi\u021bii alcaline. Exist\u0103 forme diferite ale enzimei care apar \u00een \u021besuturile normale \u0219i maligne. Enzima de fosfataz\u0103 alcalin\u0103 se g\u0103se\u0219te \u00een multe \u021besuturi \u0219i organe, \u00een special \u00een ficat, oase, intestine, rinichi \u0219i placent\u0103. Enzima de fosfataz\u0103 alcalin\u0103 func\u021bioneaz\u0103 optim la nivelul de 8.6 al pH-ului. Ca toate enzimele din corp, fosfataza alcalin\u0103 este necesar\u0103 \u00een cantit\u0103\u021bi mici pentru a declan\u0219a reac\u021biile chimice din corp. Nivelurile ridicate, anormale de ser de fosfataz\u0103 alcalin\u0103 pot indica boli ale oaselor, ficatului sau pot indica faptul c\u0103 exist\u0103 o obstruc\u021bie a c\u0103ii biliare. Fosfataza alcalin\u0103 a ficatului este produs\u0103 de celulele care consolideaz\u0103 c\u0103ile biliare din ficat. Fiecare \u021besut, cum ar fi ficatul, oasele, placenta \u0219i intestinul produce o fosfataz\u0103 alcalin\u0103 u\u0219or diferit\u0103. Aceste varia\u021bii sunt cunoscute ca \u0219i izoenzime. Tipurile diferite de fosfataz\u0103 alcalin\u0103 sunt numite \u0219i ele izoenzime.<\/p>\n

Oasele aflate \u00een cre\u0219tere au nevoie de fosfataza alcalin\u0103 pentru formarea normal\u0103. Orice condi\u021bie a cre\u0219terii oaselor va provoca astfel cre\u0219terea nivelurilor de fosfataz\u0103 alcalin\u0103 din s\u00e2nge. Aceast\u0103 stare este complet normal\u0103, precum cre\u0219terea brusc\u0103 \u00een copil\u0103rie sau vindecarea unui os rupt, uneori \u0219i cre\u0219terea nivelurilor de fosfataz\u0103 alcalin\u0103 din corp poate fi cauzat\u0103 de boli ca \u0219i cancerul, boala Paget sau rahitismul.<\/p>\n

 <\/p>\n

De ce se m\u0103soar\u0103 nivelul de fosfataz\u0103 alcalin\u0103?<\/h2>\n

Fosfataza alcalin\u0103 este m\u0103surat\u0103 pentru a verifica func\u021bionarea corect\u0103 a ficatului pacientului. \u00centr-un ficat s\u0103n\u0103tos, lichidul care con\u021bine fosfataza alcalin\u0103 \u0219i alte substan\u021be este evacuat continuu prin calea biliar\u0103. Totu\u0219i, la o boal\u0103 de ficat, calea biliar\u0103 este deseori blocat\u0103, \u0219i astfel lichidul este re\u021binut \u00een ficat. Fosfataza alcalin\u0103 poate ajunge, eventual, \u00een circula\u021bia s\u00e2ngelui. Dac\u0103 boala de ficat este de natur\u0103 obstructiv\u0103, cum ar fi colestaza, este implicat sistemul de drenaj biliar, iar fosfataza alcalin\u0103 va fi prima \u0219i va cre\u0219te prima. Totu\u0219i, dac\u0103 boala este \u00een special a celulelor ficatului sau hepatocitelor, atunci nivelul de aminotransferaze va cre\u0219te semnificativ. A\u0219adar, de ce sunt aceste enzime at\u00e2t de folositoare \u00een procesele de diferen\u021biere a tipului de boal\u0103 de ficat, fie dac\u0103 sunt colestatice sau hepatocelulare. Nivelul de fosfataz\u0103 alcalin\u0103 prezent \u00een corpul sau s\u00e2ngele unei persoane depinde de v\u00e2rsta sau sexul acestora, \u0219i poate s\u0103 varieze \u00een func\u021bie de tipul de analiz\u0103 de laborator folosit.<\/p>\n

 <\/p>\n

Standardul de preg\u0103tire<\/h2>\n

Recoltarea se efectueaz\u0103 \u00een mod normal diminea\u021ba, la spital. Nu exist\u0103 o preg\u0103tire special\u0103 necesar\u0103 pentru aceast\u0103 analiz\u0103. Doctorul v\u0103 va sf\u0103tui \u0219i recomanda dac\u0103 trebuie s\u0103 posti\u021bi \u00eenainte de analiza de s\u00e2nge. Ar trebui s\u0103 informa\u021bi doctorul dac\u0103 a\u021bi luat medicamente \u00eenainte de aceast\u0103 analiz\u0103, din moment ce unele tratamente medicale pot interfera cu rezultatele analizei.<\/p>\n

 <\/p>\n

Este aceast\u0103 evaluare periculoas\u0103 sau dureroas\u0103?<\/h2>\n

Evaluarea nu este nici dureroas\u0103, nici periculoas\u0103. Pacientul poate sim\u021bi o senza\u021bie de usturime c\u00e2nd este introdus acul \u00een bra\u021b \u0219i la luarea s\u00e2ngelui pentru analizare.<\/p>\n

 <\/p>\n

Cum este efectuat\u0103 evaluarea?<\/h2>\n

Evaluarea cuprinde simpla analizare a mostrei de s\u00e2nge.<\/p>\n","protected":false},"featured_media":0,"template":"","class_list":["post-76113","cure","type-cure","status-publish","hentry"],"yoast_head":"\nFosfataz\u0103 alcalin\u0103 - Humanitas.net<\/title>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"ro_RO\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Fosfataz\u0103 alcalin\u0103 - Humanitas.net\" \/>\n<meta property=\"og:description\" content=\"Fosfataz\u0103 alcalin\u0103 Ce este fosfataza alcalin\u0103? Fosfataza alcalin\u0103 (ALP) este o enzim\u0103 care catalizeaz\u0103 clivajul ortofosfatului din monoesterii ortofosforici \u00een condi\u021bii alcaline. Exist\u0103 forme diferite ale enzimei care apar \u00een \u021besuturile normale \u0219i maligne. Enzima de fosfataz\u0103 alcalin\u0103 se g\u0103se\u0219te \u00een multe \u021besuturi \u0219i organe, \u00een special \u00een ficat, oase, intestine, rinichi \u0219i placent\u0103. Enzima […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/humanitas-net.humweb.webiz.team\/treatments\/alkaline-phosphatase\/\" \/>\n<meta property=\"og:site_name\" content=\"Humanitas.net\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/HumanitasInternational\/\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:site\" content=\"@humanitasmilano\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/humanitas-net.humweb.webiz.team\/treatments\/alkaline-phosphatase\/\",\"url\":\"https:\/\/humanitas-net.humweb.webiz.team\/treatments\/alkaline-phosphatase\/\",\"name\":\"Fosfataz\u0103 alcalin\u0103 - Humanitas.net\",\"isPartOf\":{\"@id\":\"https:\/\/humanitas-net.humweb.webiz.team\/#website\"},\"datePublished\":\"2017-03-24T15:31:45+00:00\",\"dateModified\":\"2017-03-24T15:31:45+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/humanitas-net.humweb.webiz.team\/treatments\/alkaline-phosphatase\/#breadcrumb\"},\"inLanguage\":\"ro-RO\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/humanitas-net.humweb.webiz.team\/treatments\/alkaline-phosphatase\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/humanitas-net.humweb.webiz.team\/treatments\/alkaline-phosphatase\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/humanitas-net.humweb.webiz.team\/ro\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Trattamenti\",\"item\":\"https:\/\/humanitas-net.humweb.webiz.team\/cure\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Fosfataz\u0103 alcalin\u0103\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/humanitas-net.humweb.webiz.team\/#website\",\"url\":\"https:\/\/humanitas-net.humweb.webiz.team\/\",\"name\":\"Humanitas.net\",\"description\":\"Humanitas Hospital\",\"publisher\":{\"@id\":\"https:\/\/humanitas-net.humweb.webiz.team\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/humanitas-net.humweb.webiz.team\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"ro-RO\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/humanitas-net.humweb.webiz.team\/#organization\",\"name\":\"Humanitas\",\"url\":\"https:\/\/humanitas-net.humweb.webiz.team\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"ro-RO\",\"@id\":\"https:\/\/humanitas-net.humweb.webiz.team\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/humanitas-net.humweb.webiz.team\/wp-content\/uploads\/2025\/01\/new-humanitas-logo-1.svg\",\"contentUrl\":\"https:\/\/humanitas-net.humweb.webiz.team\/wp-content\/uploads\/2025\/01\/new-humanitas-logo-1.svg\",\"width\":1,\"height\":1,\"caption\":\"Humanitas\"},\"image\":{\"@id\":\"https:\/\/humanitas-net.humweb.webiz.team\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.facebook.com\/HumanitasInternational\/\",\"https:\/\/x.com\/humanitasmilano\"]}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Fosfataz\u0103 alcalin\u0103 - Humanitas.net","robots":{"index":"noindex","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"og_locale":"ro_RO","og_type":"article","og_title":"Fosfataz\u0103 alcalin\u0103 - Humanitas.net","og_description":"Fosfataz\u0103 alcalin\u0103 Ce este fosfataza alcalin\u0103? Fosfataza alcalin\u0103 (ALP) este o enzim\u0103 care catalizeaz\u0103 clivajul ortofosfatului din monoesterii ortofosforici \u00een condi\u021bii alcaline. Exist\u0103 forme diferite ale enzimei care apar \u00een \u021besuturile normale \u0219i maligne. Enzima de fosfataz\u0103 alcalin\u0103 se g\u0103se\u0219te \u00een multe \u021besuturi \u0219i organe, \u00een special \u00een ficat, oase, intestine, rinichi \u0219i placent\u0103. Enzima […]","og_url":"https:\/\/humanitas-net.humweb.webiz.team\/treatments\/alkaline-phosphatase\/","og_site_name":"Humanitas.net","article_publisher":"https:\/\/www.facebook.com\/HumanitasInternational\/","twitter_card":"summary_large_image","twitter_site":"@humanitasmilano","twitter_misc":{"Est. reading time":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/humanitas-net.humweb.webiz.team\/treatments\/alkaline-phosphatase\/","url":"https:\/\/humanitas-net.humweb.webiz.team\/treatments\/alkaline-phosphatase\/","name":"Fosfataz\u0103 alcalin\u0103 - Humanitas.net","isPartOf":{"@id":"https:\/\/humanitas-net.humweb.webiz.team\/#website"},"datePublished":"2017-03-24T15:31:45+00:00","dateModified":"2017-03-24T15:31:45+00:00","breadcrumb":{"@id":"https:\/\/humanitas-net.humweb.webiz.team\/treatments\/alkaline-phosphatase\/#breadcrumb"},"inLanguage":"ro-RO","potentialAction":[{"@type":"ReadAction","target":["https:\/\/humanitas-net.humweb.webiz.team\/treatments\/alkaline-phosphatase\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/humanitas-net.humweb.webiz.team\/treatments\/alkaline-phosphatase\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/humanitas-net.humweb.webiz.team\/ro\/"},{"@type":"ListItem","position":2,"name":"Trattamenti","item":"https:\/\/humanitas-net.humweb.webiz.team\/cure\/"},{"@type":"ListItem","position":3,"name":"Fosfataz\u0103 alcalin\u0103"}]},{"@type":"WebSite","@id":"https:\/\/humanitas-net.humweb.webiz.team\/#website","url":"https:\/\/humanitas-net.humweb.webiz.team\/","name":"Humanitas.net","description":"Humanitas Hospital","publisher":{"@id":"https:\/\/humanitas-net.humweb.webiz.team\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/humanitas-net.humweb.webiz.team\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"ro-RO"},{"@type":"Organization","@id":"https:\/\/humanitas-net.humweb.webiz.team\/#organization","name":"Humanitas","url":"https:\/\/humanitas-net.humweb.webiz.team\/","logo":{"@type":"ImageObject","inLanguage":"ro-RO","@id":"https:\/\/humanitas-net.humweb.webiz.team\/#\/schema\/logo\/image\/","url":"https:\/\/humanitas-net.humweb.webiz.team\/wp-content\/uploads\/2025\/01\/new-humanitas-logo-1.svg","contentUrl":"https:\/\/humanitas-net.humweb.webiz.team\/wp-content\/uploads\/2025\/01\/new-humanitas-logo-1.svg","width":1,"height":1,"caption":"Humanitas"},"image":{"@id":"https:\/\/humanitas-net.humweb.webiz.team\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/HumanitasInternational\/","https:\/\/x.com\/humanitasmilano"]}]}},"acf":[],"_links":{"self":[{"href":"https:\/\/humanitas-net.humweb.webiz.team\/ro\/wp-json\/wp\/v2\/cure\/76113","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/humanitas-net.humweb.webiz.team\/ro\/wp-json\/wp\/v2\/cure"}],"about":[{"href":"https:\/\/humanitas-net.humweb.webiz.team\/ro\/wp-json\/wp\/v2\/types\/cure"}],"wp:attachment":[{"href":"https:\/\/humanitas-net.humweb.webiz.team\/ro\/wp-json\/wp\/v2\/media?parent=76113"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}