{"id":72540,"date":"2019-01-31T14:12:53","date_gmt":"2019-01-31T14:12:53","guid":{"rendered":"http:\/\/humanitasnet-new.local\/malattie\/pyoderma-gangrenosum-3\/"},"modified":"2025-01-13T03:13:58","modified_gmt":"2025-01-13T03:13:58","slug":"pyoderma-gangrenosum","status":"publish","type":"disease","link":"https:\/\/humanitas-net.humweb.webiz.team\/fr\/diseases\/pyoderma-gangrenosum\/","title":{"rendered":"Pyoderma gangrenosum"},"content":{"rendered":"<p>Le pyoderma gangrenosum (ou phag\u00e9d\u00e9nisme g\u00e9om\u00e9trique) est une r\u00e9action cutan\u00e9e rare \u00e0 une maladie ou \u00e0 une affection qui provoque des ulc\u00e8res cutan\u00e9s douloureux. Il s&#8217;agit d&#8217;une affection qui entra\u00eene la n\u00e9crose des tissus, ce qui provoque des ulc\u00e8res profonds qui apparaissent habituellement sur les jambes. Malgr\u00e9 son nom similaire, Pyoderma gangrenosum n&#8217;est pas apparent\u00e9 \u00e0 la gangr\u00e8ne.<\/p>\n<p>Pyoderma gangrenosum commence habituellement par une petite bosse rouge sur la peau, qui peut ressembler \u00e0 une morsure d&#8217;araign\u00e9e, un petit bouton, une bosse rouge ou une ampoule de sang. En quelques jours, cette bosse peut se transformer en une grande plaie ouverte douloureuse. En d&#8217;autres termes, la peau se d\u00e9compose alors en un ulc\u00e8re douloureux, qui peut suinter du liquide. Lorsque les ulc\u00e8res apparaissent, ils peuvent rapidement devenir plus gros et plus profonds et peuvent entra\u00eener des plaies chroniques. Si le patient a plusieurs ulc\u00e8res, ils peuvent grandir et fusionner en un seul ulc\u00e8re plus grand.<\/p>\n<p>Pyoderma gangrenosum affecte habituellement les jambes, bien qu&#8217;il puisse affecter n&#8217;importe quel secteur de peau, y compris autour de la t\u00eate et du cou, des membres sup\u00e9rieurs et des organes g\u00e9nitaux. \u00c0 l&#8217;occasion, il se d\u00e9veloppe autour du site d&#8217;une blessure ou d&#8217;une plaie chirurgicale, comme une stomie. Bien que ces blessures entra\u00eenent rarement la mort, elles peuvent causer de la fi\u00e8vre, des douleurs intenses et des cicatrices.<\/p>\n<p>&nbsp;<\/p>\n<h2 id=\"causes\">Causes<\/h2>\n<p>Ii n&#8217;est pas certain de ce qui cause pyoderma gangrenosum, mais il semble \u00eatre un trouble du syst\u00e8me immunitaire. De plus, il est souvent associ\u00e9 \u00e0 des affections inflammatoires, comme la colite ulc\u00e9reuse et la maladie de Crohn. Si une personne souffre de pyoderma gangrenosum, un nouveau traumatisme cutan\u00e9, comme une coupure ou une plaie perforante, peut entra\u00eener la formation de nouveaux ulc\u00e8res. Cette tendance des nouveaux ulc\u00e8res \u00e0 se former \u00e0 partir d&#8217;un traumatisme, y compris la chirurgie, est connue sous le nom de pathergie.<\/p>\n<p>&nbsp;<\/p>\n<h2 id=\"facteurs-de-risque\">Facteurs de risque<\/h2>\n<p>Pyoderma gangrenosum est le plus commun chez les personnes ag\u00e9es de 40 \u00e0 50 ans, mais peut survenir \u00e0 tout \u00e2ge. Les personnes atteintes de certains troubles sous-jacents, comme la maladie inflammatoire intestinale ou la polyarthrite rhumato\u00efde, sont \u00e9galement plus expos\u00e9es au risque de gangrenosum pyoderma. Il est \u00e9galement associ\u00e9 \u00e0 des conditions inflammatoires, notamment :<\/p>\n<ul>\n<li>Colite ulc\u00e9reuse<\/li>\n<li>Maladie de Crohn<\/li>\n<li>Polyarthrite rhumato\u00efde<\/li>\n<li>Complications<\/li>\n<li>Les ulc\u00e8res associ\u00e9s \u00e0 Pyoderma gangrenosum laissent souvent des cicatrices.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h2 id=\"prevention\">Pr\u00e9vention<\/h2>\n<p>Personne ne peut totalement emp\u00eacher Pyoderma gangrenosum. Si quelqu&#8217;un est atteint de la maladie, il ou elle devrait essayer d&#8217;\u00e9viter de blesser la peau. Une blessure ou un traumatisme cutan\u00e9 peut provoquer la formation de nouveaux ulc\u00e8res. Bien qu&#8217;elle ne soit pas enti\u00e8rement efficace, la prise en charge de tout trouble sous-jacent qui pourrait causer les ulc\u00e8res peut \u00e9galement s&#8217;av\u00e9rer utile.<\/p>\n","protected":false},"featured_media":0,"template":"","class_list":["post-72540","disease","type-disease","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.3 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Pyoderma gangrenosum - Humanitas.net<\/title>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Pyoderma gangrenosum - Humanitas.net\" \/>\n<meta property=\"og:description\" content=\"Le pyoderma gangrenosum (ou phag\u00e9d\u00e9nisme g\u00e9om\u00e9trique) est une r\u00e9action cutan\u00e9e rare \u00e0 une maladie ou \u00e0 une affection qui provoque des ulc\u00e8res cutan\u00e9s douloureux. 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